I would usually be sad to see another original RPG go 5e compatible but Neuroshima was infamously poorly designed ruleset, possibly worse than Shadowrun. I probably won’t be running it, but may steal statblocks for my 5e game if I need weird stuff again.
Whats wrong with 5e?
Its a system that does some things really well and some things very poorly, like every other TTRPG. Thus trying to force 5e to do things it was never meant to often either results in a bad experience overall, or basically not using the 5e rules at all.
Hasbro is what’s wrong with 5e. The rest of it is fairly decent.
It’s too popular for the people who want to play other systems.
Where do you want to start? The player mechanics are way outdated and overcomplicated for what it wants to be, the GM mechanics are functionally nonexistant, the lore is cliched at best and still incredibly bigoted in many areas, the better adventures are just rehashes of 2e and 3.x adventures and still need entire communities dedicated to making them runnable, it’s unbalanced until you get to about level 10 at which point it becomes unplayable, and without pirating it’s incredibly expensive.
Trying to strap every possible setting and mechanic onto a fantasy rule system was one of the issues 3.x ended up with, and 5e hasn’t been designed to solve that.