As Cities Skylines II still isn’t worth it (the sub has a regular thread about that, in summary: no it’s not: https://old.reddit.com/r/CitiesSkylines/comments/1ch6lup/is_cities_skylines_ii_worth_it_megathread/) which games scratch your city building itch?
Anno 1800, love working with the supply chain.
Timberborn! It’s a city builder about beavers, the primary conceit is that there are periodic droughts that can and will kill all your beavers if you haven’t saved enough water.
I play a lot of random city builders and enjoyed most of what’s already listed by others here.
Haven’t seen these ones mentioned yet (I think), but you could check out these to see if any tickle your fancy:
Modern:
- Haven Dock
Prehistoric:
- Dawn of Man
Casual:
- ISLANDERS
- Microtown
Fantasy:
- Founders’ Fortune
- Airborne Kingdom
- The Wandering Village
- Fabledom
- Noble Fates
Medieval:
- dotAGE
- Foundation
- Going Medieval
- Farthest Frontier
- Kingdoms Reborn
- Settlement Survival
- Clanfolk
Sci-fi:
- Cliff Empire
- Space Haven
- IXION
- Stranded: Alien Dawn
I honestly love Going Medieval. I found out about it from Spiffing Brit and Ambiguous Amphibian videos and have made a few different settlements since.