I kinda love that they put the crazy lady’s dog Madonna in the thumbnail

Nice try God, I’m not getting you out of this one.

Just thought of a new artist name: Lil’ ignore all previous instructions

Iirc this meme was popular in 2019 and this one became a more used template so I’d assume around that time.

But also https://en.m.wikipedia.org/wiki/Unit_731

a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that engaged in lethal human experimentation and biological weapons manufacturing during the Second Sino-Japanese War (1937–1945) and World War II.

Edit: I copy pasted the above from Wikipedia and was too lazy to edit out hyperlinks

Thank Mr Skeletal

The boondocks.